Search results for "PsyArXiv|Psychiatry"

Individualized Template MRI Is a Valid and Reliable Alternative to Individual MRI for Spatial Tracking in Navigated TMS Studies in Healthy Subjects

2020

Objectives: Navigated transcranial magnetic stimulation (nTMS) provides significant benefits over classic TMS. Yet, the acquisition of individual structural magnetic resonance images (MRIindividual) is a time-consuming, expensive, and not feasible prerequisite in all subjects for spatial tracking and anatomical guidance in nTMS studies. We hypothesize that spatial transformation can be used to adjust MRI templates to individual head shapes (MRIwarped) and that TMS parameters do not differ between nTMS using MRIindividual or MRIwarped.Materials and Methods: Twenty identical TMS sessions, each including four different navigation conditions, were conducted in 10 healthy subjects (one female, 2…

A time estimation task as a possible measure of emotions: difference depending on the nature of the stimulus used

2015

Objective: Time perception is fundamental for human experience. A topic which has attracted the attention of researchers for long time is how the stimulus sensory modality (e.g., images vs. sounds) affects time judgments. However, so far, no study has directly compared the effect of two sensory modalities using emotional stimuli on time judgments. Methods: In the present two studies, healthy participants were asked to estimate the duration of a pure sound preceded by the presentation of odors vs. emotional videos as priming stimuli (implicit emotion-eliciting task). During the task, skin conductance (SC) was measured as an index of arousal. Results: Olfactory stimuli resulted in an increase…

Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology

2020

Amyloids are fibrillar protein aggregates associated with diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), type II diabetes and Creutzfeldt–Jakob disease. The process of amyloid polymerization involves three pathological protein transformations; from natively folded conformation to the cross-β conformation, from biophysically soluble to insoluble, and from biologically functional to non-functional. While amyloids share a similar cross-β conformation, the biophysical transformation can either take place spontaneously via a homogeneous nucleation mechanism (HON) or catalytically on an exogenous surface via a heterogeneous nucleation mechanism (HEN). Here, we postulate that…

An aphasia research agenda–a consensus statement from the collaboration of aphasia trialists

2021

Coordination of international aphasia research would minimise duplication of effort, support synergistic international activities across languages and multidisciplinary perspectives, and promote high-quality conduct and reporting of aphasia research, thereby increasing the relevance, transparency, and implementation of findings. The Collaboration of Aphasia Trialists (CATs) sought to develop an aphasia research agenda to direct future research activities, based on priorities shared by people with aphasia, family members, and healthcare professionals. Our established international research network spanning 33 countries contributed to this activity. Research literature reporting the prioritie…

Koulukotisijoitus - nuoren toinen mahdollisuus? : mielenterveyden häiriöiden, oppimisvaikeuksien ja perheongelmien kirjo kehittämishaasteena

2011

Study engagement and burnout profiles among Finnish higher education students

2017

A person-oriented approach was applied to identify profiles of study engagement and burnout (i.e., exhaustion, cynicism, inadequacy) in higher education in a large and representative sample of 12,394 higher education students at different phases of their studies in universities and polytechnics in Finland. Four profiles were identified: Engaged (44%), engaged-exhausted (30%) inefficacious (19%) and burned-out (7%). The engaged students had the most positive engagement accompanied with the least burnout symptoms compared to other groups. The engaged-exhausted students experienced emotional exhaustion simultaneously with academic engagement. The inefficacious group had heightened experience o…

Adolescents’ Stress and Depressive symptoms and Their Associations with Psychological Flexibility before Educational Transition

2023

Introduction: Relatively little is known about individual differences in adolescent psychological flexibility and its associations with symptoms of stress and depression. This study examined different profiles of adolescent stress and depressive symptoms and their associations with developing psychological flexibility before the critical educational transition. Methods: The data were derived from a general sample of 740 Finnish ninth-grade adolescents (Mage = 15.7 years, 57% female) who were assessed twice during the final grade of their basic education. The data were analyzed using growth mixture modeling. Results: Four profiles of stress and depressive symptoms were identified during a sc…

Does predictability matter? Effects of cue predictability on neurocognitive mechanisms underlying prospective memory

2015

Prospective memory (PM) represents the ability to successfully realize intentions when the appropriate moment or cue occurs. In this study, we used event-related potentials (ERPs) to explore the impact of cue predictability on the cognitive and neural mechanisms supporting PM. Participants performed an ongoing task and, simultaneously, had to remember to execute a pre-specified action when they encountered the PM cues. The occurrence of the PM cues was predictable (being signalled by a warning cue) for some participants and was completely unpredictable for others. In the predictable cue condition, the behavioural and ERP correlates of strategic monitoring were observed mainly in the ongoing…

La licantropía y el efialtes en la literatura médica griega: los testimonios de Areteo, Galeno, Posidonio y Aecio de Amida, Oribasio y Actuario (más …

2018

Textos médicos de las épocas imperial y bizantina nos proporcionan alguna información sobre las patologías de la licantropía y el llamado efialtes, que son tratadas correlativamente y que presentan algunas características comunes a ambas, si bien es la primera la que recibe mayor atención. El presente trabajo comprende brevemente los pasajes de mayor interés, acompañados de su traducción y de un somero comentario que atiende a la problemática filológica, histórica y médica. Se concluye el acierto de la medicina griega al relacionar ambas afecciones con la estabilidad psiquiátrica del paciente, exactamente como lo hace la medicina moderna, sin por ello dejar de lado el establecimiento de una…

‘I Can’t Breathe’: Anxiety and Emotion Awareness in Older Adolescents at The Time of Covid-19

2020

The COVID-19 appears as a catastrophic health risk with psychological, emotional, social and relational implications. From the early stages of the virus spread, the elderly population was identified as the most vulnerable and the health authorities have rightly focused on such frailest population. Conversely, less attention was paid to emotional and psychological dimension of children and adolescents. Actually, they were less at risk quoad vitam or quoad valetudinem, nevertheless they had to face a reality of anxiety, fears and uncertainties. The current study investigated state anxiety and emotion awareness in a healthy sample of older adolescents, 84 females and 64 males, aged 17 to 19, d…